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View Stirlingsays's Profile Stirlingsays Flag 21 Dec 20 1.52am Send a Private Message to Stirlingsays Holmesdale Online Elite Member Add Stirlingsays as a friend

Firstly I'd say each individual, in most situations, should get to decide for themselves with no punishments...well in a free country that should be the case.

That having been said, my own view is that I'd recommend the elderly and ill take this vaccine. As it's probable that the benefit outweighs the unknowns.

However, for the young, fit and healthy I'm not going to come on here and say I would recommend taking any vaccine that has been developed in ten months. Common sense tells you that you are taking part in a beta test.

The lack of a guarantee on fertility should be significant and unacceptable for young people: that is not small fry.....At this stage they just aren't sure.

The number of people who have died from this vaccine who were young and didn't have any underlying health conditions is very low: For them, It is more risky to drive to work.

However, ultimately we are all responsible for the decisions we take.

 


'Who are you and how did you get in here? I'm a locksmith. And, I'm a locksmith.' (Leslie Nielsen)

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View Mapletree's Profile Mapletree Flag Croydon 21 Dec 20 8.50am Send a Private Message to Mapletree Add Mapletree as a friend

Originally posted by Stirlingsays

Firstly I'd say each individual, in most situations, should get to decide for themselves with no punishments...well in a free country that should be the case.

That having been said, my own view is that I'd recommend the elderly and ill take this vaccine. As it's probable that the benefit outweighs the unknowns.

However, for the young, fit and healthy I'm not going to come on here and say I would recommend taking any vaccine that has been developed in ten months. Common sense tells you that you are taking part in a beta test.

The lack of a guarantee on fertility should be significant and unacceptable for young people: that is not small fry.....At this stage they just aren't sure.

The number of people who have died from this vaccine who were young and didn't have any underlying health conditions is very low: For them, It is more risky to drive to work.

However, ultimately we are all responsible for the decisions we take.

Another post, another red herring. You are forgiven for not taking the vaccine as there is no guarantee it won’t turn you purple

Where is your evidence of any genuine concern on fertility?

Catching the virus can, however, affect male fertility.

If young people don’t have the vaccine the virus will continue unabated and we are no further forward.

 

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View Hrolf The Ganger's Profile Hrolf The Ganger Flag 21 Dec 20 10.34am Send a Private Message to Hrolf The Ganger Add Hrolf The Ganger as a friend

Originally posted by Mapletree

Stone me.

That won't be introduced until 2025.

 

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View Stirlingsays's Profile Stirlingsays Flag 21 Dec 20 12.02pm Send a Private Message to Stirlingsays Holmesdale Online Elite Member Add Stirlingsays as a friend

Originally posted by Mapletree

Another post, another red herring. You are forgiven for not taking the vaccine as there is no guarantee it won’t turn you purple

Where is your evidence of any genuine concern on fertility?

Catching the virus can, however, affect male fertility.

If young people don’t have the vaccine the virus will continue unabated and we are no further forward.


You have added nothing that changes my post.

On the government's website it says, 'It is unknown whether COVID-19 mRNA Vaccine BNT162b2 has an impact on fertility'.

Your suggestion that this virus affects male fertility is not officially backed. Indeed, only one study suggested a long term impact on less than 20 percent of men: the evidence isn't there.....similar to this vaccine.

If this vaccine works in further reducing deaths amongst the elderly I certainly disagree with your statement that you require universal uptake for effectivity.

Edited by Stirlingsays (21 Dec 2020 12.07pm)

 


'Who are you and how did you get in here? I'm a locksmith. And, I'm a locksmith.' (Leslie Nielsen)

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View Hrolf The Ganger's Profile Hrolf The Ganger Flag 21 Dec 20 12.40pm Send a Private Message to Hrolf The Ganger Add Hrolf The Ganger as a friend

Originally posted by Stirlingsays


You have added nothing that changes my post.

On the government's website it says, 'It is unknown whether COVID-19 mRNA Vaccine BNT162b2 has an impact on fertility'.

Your suggestion that this virus affects male fertility is not officially backed. Indeed, only one study suggested a long term impact on less than 20 percent of men: the evidence isn't there.....similar to this vaccine.

If this vaccine works in further reducing deaths amongst the elderly I certainly disagree with your statement that you require universal uptake for effectivity.


Edited by Stirlingsays (21 Dec 2020 12.07pm)

Yes, I'm not sure why perfectly healthy young people who are not at more than a tiny risk should need to inoculate in the current circumstances. Were the virus to suddenly become more deadly to more people, then we could have a rethink.

 

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View Stirlingsays's Profile Stirlingsays Flag 21 Dec 20 1.14pm Send a Private Message to Stirlingsays Holmesdale Online Elite Member Add Stirlingsays as a friend

Originally posted by Hrolf The Ganger

Yes, I'm not sure why perfectly healthy young people who are not at more than a tiny risk should need to inoculate in the current circumstances. Were the virus to suddenly become more deadly to more people, then we could have a rethink.

Seconded.

Certainty has always been what people want in life, that way they can navigate decisions better without much thought. Still, we know that real life doesn't work like that and you make decisions based upon probabilities.

I think most of us here support the individual's right to make their own decisions on what goes into their body.

 


'Who are you and how did you get in here? I'm a locksmith. And, I'm a locksmith.' (Leslie Nielsen)

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View Mapletree's Profile Mapletree Flag Croydon 21 Dec 20 1.25pm Send a Private Message to Mapletree Add Mapletree as a friend

Originally posted by Stirlingsays

Seconded.

Certainty has always been what people want in life, that way they can navigate decisions better without much thought. Still, we know that real life doesn't work like that and you make decisions based upon probabilities.

I think most of us here support the individual's right to make their own decisions on what goes into their body.

God you two are being stupid

If we want the virus to circulate less then we need to prevent young people getting it. There have been periods of time when it was largely younger people driving the epidemic.

For this reason the silly old Government has been considering a schools-based vaccination programme. What dummies eh? Why waste all that money when clever people like you realise it's just not a problem if the virus continually circulates.

Or, to put it another way. We end up with a crippled economy until just about everyone has had the disease, with older people having the vaccine so not dying.

That would suit your Russian paymasters extremely well. Finish off the destruction of our economy following the extremely good start they managed to precipitate with their support of the Brexit process.

 

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View Mapletree's Profile Mapletree Flag Croydon 21 Dec 20 1.31pm Send a Private Message to Mapletree Add Mapletree as a friend

Originally posted by Stirlingsays


You have added nothing that changes my post.

On the government's website it says, 'It is unknown whether COVID-19 mRNA Vaccine BNT162b2 has an impact on fertility'.

Your suggestion that this virus affects male fertility is not officially backed. Indeed, only one study suggested a long term impact on less than 20 percent of men: the evidence isn't there.....similar to this vaccine.

If this vaccine works in further reducing deaths amongst the elderly I certainly disagree with your statement that you require universal uptake for effectivity.

Edited by Stirlingsays (21 Dec 2020 12.07pm)

When I think about semen, I think of Seymen

''To gain viral entry, SARS-CoV-2 uses a surface structure called the spike protein to bind to the ACE2 receptor present on host cells.

Studies have found that ACE2 is expressed in spermatogonia, Leydig cells, and Sertoli cells.

One study that used electron microscopy to examine post-mortem tissues from the testes of twelve COVID-19 patients demonstrated swelling, vacuolation, and cytoplasmic dilution in the Sertoli cells and a reduction in the number of Leydig cells, compared with patients who did not have COVID-19.

Some studies have also demonstrated increased levels of the autophagy receptor SQSTM1 in cells infected with SARS-CoV-2, indicating a fall in autophagy flux.

"As a result, SARS-CoV-2 may cause male reproductive disorders by regulating the level of autophagy in male germ cells," writes Seymen.

Researchers have also proposed that an increase in testicular temperature as an indirect effect of inflammation has negative impacts on the testes among COVID-19 patients.

Seymen discusses the role that TMPRSS2 may play in SARS-CoV-2 infection of the prostate.

One study found that this enzyme, which cleaves the spike protein in preparation for virus and host membrane fusion, is highly expressed in the prostate's epithelium.

This gland secretes prostate fluid, one of the main components of the seminal fluid. Muscles within the gland are responsible for pushing the seminal fluid through the urethra during ejaculation.

The high expression of TMPRSS2 within the prostate could increase the likelihood of SARS-CoV-2 infection in this gland, which may affect its ability to secrete these fluids, says Seymen.''

 

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View Stirlingsays's Profile Stirlingsays Flag 21 Dec 20 1.31pm Send a Private Message to Stirlingsays Holmesdale Online Elite Member Add Stirlingsays as a friend

So Hrolf, first we are being stupid and then later on we have Russian paymasters.

I reckon all these 16 hour shifts Maple does are affecting his noggin.

 


'Who are you and how did you get in here? I'm a locksmith. And, I'm a locksmith.' (Leslie Nielsen)

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View Stirlingsays's Profile Stirlingsays Flag 21 Dec 20 1.39pm Send a Private Message to Stirlingsays Holmesdale Online Elite Member Add Stirlingsays as a friend


Once again, your cut and paste isn't officially backed. Government has not listed this virus as a threat to fertility.

You are encouraging young people to involve themselves in a beta test.

I support people in making their own minds up and I would never criticise that.

However, when it comes to young people, especially women, I regard it as ethnically irresponsible to be so fervent that they should take the vaccine.

 


'Who are you and how did you get in here? I'm a locksmith. And, I'm a locksmith.' (Leslie Nielsen)

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View Mapletree's Profile Mapletree Flag Croydon 21 Dec 20 1.41pm Send a Private Message to Mapletree Add Mapletree as a friend

Originally posted by Stirlingsays

You have added nothing that changes my post.

On the government's website it says, 'It is unknown whether COVID-19 mRNA Vaccine BNT162b2 has an impact on fertility'.

Your suggestion that this virus affects male fertility is not officially backed. Indeed, only one study suggested a long term impact on less than 20 percent of men: the evidence isn't there.....similar to this vaccine.

If this vaccine works in further reducing deaths amongst the elderly I certainly disagree with your statement that you require universal uptake for effectivity.

Edited by Stirlingsays (21 Dec 2020 12.07pm)

I just love it when you try to use facts.

Full Fact is interesting on the female fertility point


We’ve been asked by a number of readers about claims that the Pfizer/BioNTech Covid-19 vaccine, which has been approved for use in the UK, could lead to infertility in women.

The reason given for this is that the vaccine works by igniting an immune response to a spike protein on the Covid-19 virus’ surface, and that this immune response could also attack similar proteins that make up the placenta, and therefore reduce fertility in women.

But there’s no evidence this is the case.

Where did this claim come from?
The origins of this claim stems from a protein on the surface of the SARS-CoV-2 virus (the virus which causes Covid-19), called a spike protein. This spike protein helps the virus enter cells and is also one of the ways the human body recognises a virus and knows to let its immune cells attack it.

The Pfizer vaccine works by giving the body the instructions on how to make this spike protein, so it can generate an immune response that attacks the virus via the spike protein faster and more effectively if it is later infected.

The building blocks of proteins are called amino acids, and it’s sequences of those that make up different proteins.

A small part of this spike protein resembles a part of another protein vital for the formation of the placenta, called syncytin-1. But the sequence of amino acids that are similar in syncytin-1 and the SARS-CoV-2 spike protein is quite short.

But only two very small parts of these proteins look the same—it’s not the whole protein—and therefore realistically the body’s immune system is not likely to confuse the two, and attack syncytin-1 rather than the spike protein on SARS-CoV-2 and stop a placenta forming.

What do the experts say?
Virology professor Ian Jones at the University of Reading told Full Fact, via the Science Media Centre, that the spike protein and syncytin-1 don’t look similar enough for the same antibodies that the body would create as an immune response to the vaccine, to bind to and attack syncytin.

He said syncytin-1 is “completely unrelated to the SARS [spike] protein” and the risk of infertility is “therefore essentially fictitious.”

Professor Jonathan Stoye, Virologist at the Francis Crick Institute, told Full Fact these proteins are not identical, as some have claimed.

On whether the vaccine could cause an immune reaction to the syncytin-1 protein vital for placenta formation, he said: “I would never say never, but the possibility is vanishingly small.”

What did the trials show?
There also isn’t any evidence from trials of the Pfizer vaccine that it affects fertility.

As the vaccine stimulates an immune response to the spike protein, if it did affect fertility we might also expect to see Covid-19 infections affecting this too, as the body should produce a similar immune response if infected. But we don’t. Although it has been suggested that Covid-19 cases seem to be more severe in pregnant women, there doesn’t seem to be evidence that Covid-19 causes women to lose their pregnancy, or struggle to get pregnant later.

The government currently says that the Pfizer vaccine “has not yet been assessed in pregnancy, so it has been advised that until more information is available, those who are pregnant should not have this vaccine.”

A number of Facebook posts point to UK government-published guidance on this vaccine, that says: “It is unknown whether COVID-19 mRNA Vaccine BNT162b2 has an impact on fertility.”

Although we haven’t had years to watch what happens after people get the vaccine, this doesn’t mean there’s any evidence this vaccine might impact fertility. It just means that hasn’t been explicitly studied.


I see the Telegraph has a headline on this but I can't read the story. The CDC specifically says:

'Women who are trying to become pregnant do not need to avoid pregnancy after receiving an mRNA COVID-19 vaccine'

We also know that ,based on how mRNA vaccines work, experts believe they are unlikely to pose a risk for people who are pregnant'

And finally

'Observational data demonstrate that, while the chances for these severe health effects are infrequent, pregnant people with COVID-19 have an increased risk of severe illness, including illness that results in ICU admission, mechanical ventilation, and death. Additionally, pregnant people with COVID-19 might be at increased risk of adverse pregnancy outcomes, such as preterm births.'


Let me repeat, by being a conduit for mis-information you discourage some people from taking the vaccine. If you do that then you are going to be responsible for deaths. Why do you choose to spread your rubbish all the time. Take responsibility dammit.

 

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View Mapletree's Profile Mapletree Flag Croydon 21 Dec 20 1.43pm Send a Private Message to Mapletree Add Mapletree as a friend

Originally posted by Stirlingsays


Once again, your cut and paste isn't officially backed. Government has not listed this virus as a threat to fertility.

You are encouraging young people to involve themselves in a beta test.

I support people in making their own minds up and I would never criticise that.

However, when it comes to young people, especially women, I regard it as ethnically irresponsible to be so fervent that they should take the vaccine.

As usual you didn't really understand the facts I presented so distract

Weird for someone that teaches science based subjects

And no, you were not supporting people making up their own minds because you choose to sow the seeds of doubt without any scientific justification. You do this regularly. Unfortunately it does have a cumulative effect on people who don't realise you are talking out of your bottom.

Edited by Mapletree (21 Dec 2020 1.45pm)

 

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